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DEVELOPMENT OF AREA UNDER CURVE SPECTROPHOTOMETRIC METHOD FOR QUALITATIVE ANALYSIS OF ESOMEPRAZOLE

Authors

Mr. Rathod Laxman , Ms.Katagaon Supriya, Dr. Rajmani Shabadi
1. Department of Pharmaceutical Quality Assurance, dept of pharmacutical quality assurance, BLDEA’S SSM College Of Pharmacy & RC Vijayapura, Karnataka India

Abstract

The drugs Esomeprazole was dissolved in DMF using the Area under curve method in the simultaneous estimation spectrophotometric approach. 285?350 nm wavelength range. Esomeprazole is bound with Beer's law in the concentration range of 10, 15, 20 ,25, 30µg/ml. Using recovery studies, the proposed method's precision was verified, and the outcomes were validated in accordance with ICH recommendations. The findings of the analysis have been statistically corroborated by recovery studies. The technique worked well in evaluating Esomeprazole in tablet dose form without interfering with common excipients.

Keywords

Esomeprazole, DMF,Area Under Curve method, Spectrophotometric method

How to Cite:

Mr. Rathod Laxman , Ms.Katagaon Supriya, Dr. Rajmani Shabadi , DEVELOPMENT OF AREA UNDER CURVE SPECTROPHOTOMETRIC METHOD FOR QUALITATIVE ANALYSIS OF ESOMEPRAZOLE , Volume 10 , Issue 2, february 2025, EPRA International Journal of Research & Development (IJRD),